
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
TMED1
Introduction
Transmembrane emp24 domain-containing protein 1 is a protein that in humans is encoded by the TMED1 gene.[1][2][3]
The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1). This protein lacks any similarity to other interleukin 1 ligands. The functional significance of its interaction with IL1RL1 is not known.[3]
References
References
- ↑ Chan WL, Pejnovic N, Lee CA, Al-Ali NA (Jul 2001). “Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes”. J Immunol. 167 (3): 1238–44. doi:10.4049/jimmunol.167.3.1238. PMID 11466339.
- ↑ Gayle MA, Slack JL, Bonnert TP, Renshaw BR, Sonoda G, Taguchi T, Testa JR, Dower SK, Sims JE (Jun 1996). “Cloning of a putative ligand for the T1/ST2 receptor”. J Biol Chem. 271 (10): 5784–9. doi:10.1074/jbc.271.10.5784. PMID 8621446.
- ↑ 3.0 3.1 “Entrez Gene: TMED1 transmembrane emp24 protein transport domain containing 1”.
Further reading
Further reading
- Rual JF, Venkatesan K, Hao T, et al. (2005). “Towards a proteome-scale map of the human protein-protein interaction network”. Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Colland F, Jacq X, Trouplin V, et al. (2004). “Functional Proteomics Mapping of a Human Signaling Pathway”. Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
- Grimwood J, Gordon LA, Olsen A, et al. (2004). “The DNA sequence and biology of human chromosome 19”. Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
