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TMEM219

Introduction

Transmembrane protein 219 also known as insulin-like growth factor-binding protein 3 receptor or IGFBP-3R is a protein that in humans is encoded by the TMEM219 gene.[1] IGFBP-3R acts as a cell death receptor for IGFBP3.[2]

References

  1. ↑ “Entrez Gene: Transmembrane protein 219”.
  2. ↑ Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y (September 2010). “Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer”. J. Biol. Chem. 285 (39): 30233–46. doi:10.1074/jbc.M110.122226. PMC 2943278. PMID 20353938.