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TNRC6B

Introduction

Trinucleotide repeat-containing gene 6B protein is a protein that in humans is encoded by the TNRC6B gene.[1]

Interactions

Interactions

TNRC6B has been shown to interact with EIF2C2.[2] It is also known to associate with argonaute proteins and has been shown to be required for miRNA-guided gene silencing in HeLa cells.[3]

References

References

  1. ↑ “Entrez Gene: TNRC6B trinucleotide repeat containing 6B”.
  2. ↑ Till S, Lejeune E, Thermann R, Bortfeld M, Hothorn M, Enderle D, Heinrich C, Hentze MW, Ladurner AG (October 2007). “A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain”. Nat. Struct. Mol. Biol. 14 (10): 897–903. doi:10.1038/nsmb1302. PMIDΒ 17891150.
  3. ↑ Meister G, Landthaler M, Peters L, Chen PY, Urlaub H, LΓΌhrmann R, Tuschl T (December 2005). “Identification of novel argonaute-associated proteins”. Curr. Biol. 15 (23): 2149–55. doi:10.1016/j.cub.2005.10.048. PMIDΒ 16289642.
Further reading

Further reading