Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
TRANK1
Introduction
Tetratricopeptide repeat and ankyrin repeat containing 1 is a protein that in humans is encoded by the TRANK1 gene.[1]
Disease Linkage
Disease Linkage
Through a Genome-wide association study, TRANK1 has been relationed with the Bipolar disorder.[2]
References
References
- ↑ “Entrez Gene: Tetratricopeptide repeat and ankyrin repeat containing 1”.
- ↑ Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, et al. (March 2014). “Genome-wide association study reveals two new risk loci for bipolar disorder”. Nature Communications. 5: 3339. doi:10.1038/ncomms4339. PMID 24618891.
Further reading
Further reading
- Goes FS, Hamshere ML, Seifuddin F, Pirooznia M, Belmonte-Mahon P, Breuer R, et al. (October 2012). “Genome-wide association of mood-incongruent psychotic bipolar disorder”. Translational Psychiatry. 2 (10): e180. doi:10.1038/tp.2012.106. PMCÂ 3565814. PMIDÂ 23092984.
- Chen DT, Jiang X, Akula N, Shugart YY, Wendland JR, Steele CJ, et al. (February 2013). “Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder”. Molecular Psychiatry. 18 (2): 195–205. doi:10.1038/mp.2011.157. PMID 22182935.