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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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TUBB3

Introduction

Tubulin, beta 3, also known as TUBB3, is a human gene.[1]

References

References

  1. ↑ “Entrez Gene: TUBB3 tubulin, beta 3”.
Further reading

Further reading

  • Venter JC (1993). “Identification of new human receptor and transporter genes by high throughput cDNA (EST) sequencing”. J. Pharm. Pharmacol. 45 Suppl 1: 355–60. PMID 8098743.
  • Burgoyne RD, Cambray-Deakin MA, Lewis SA; et al. (1989). “Differential distribution of beta-tubulin isotypes in cerebellum”. EMBO J. 7 (8): 2311–9. PMID 2461292.
  • Vinores SA, Derevjanik NL, Mahlow J; et al. (1995). “Class III beta-tubulin in human retinal pigment epithelial cells in culture and in epiretinal membranes”. Exp. Eye Res. 60 (4): 385–400. PMID 7789418.
  • Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1–2): 171–4. PMID 8125298.
  • Khan IA, Ludueña RF (1996). “Phosphorylation of beta III-tubulin”. Biochemistry. 35 (12): 3704–11. doi:10.1021/bi951247p. PMID 8619990.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). “Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library”. Gene. 200 (1–2): 149–56. PMID 9373149.
  • Ranganathan S, Dexter DW, Benetatos CA, Hudes GR (1998). “Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents”. Biochim. Biophys. Acta. 1395 (2): 237–45. PMID 9473684.
  • Watts NR, Sackett DL, Ward RD; et al. (2000). “HIV-1 rev depolymerizes microtubules to form stable bilayered rings”. J. Cell Biol. 150 (2): 349–60. PMID 10908577.
  • Sánchez Más J, Olivares Sánchez C, Ghanem G; et al. (2003). “Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function”. Eur. J. Biochem. 269 (24): 6133–41. PMID 12473109.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Chen D, Wang M, Zhou S, Zhou Q (2004). “HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim”. EMBO J. 21 (24): 6801–10. PMID 12486001.
  • Rosell R, Scagliotti G, Danenberg KD; et al. (2003). “Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer”. Oncogene. 22 (23): 3548–53. doi:10.1038/sj.onc.1206419. PMID 12789263.
  • Hari M, Yang H, Zeng C; et al. (2004). “Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel”. Cell Motil. Cytoskeleton. 56 (1): 45–56. doi:10.1002/cm.10132. PMID 12905530.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Campbell GR, Pasquier E, Watkins J; et al. (2005). “The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis”. J. Biol. Chem. 279 (46): 48197–204. doi:10.1074/jbc.M406195200. PMID 15331610.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Mozzetti S, Ferlini C, Concolino P; et al. (2005). “Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients”. Clin. Cancer Res. 11 (1): 298–305. PMID 15671559.
  • de Mareuil J, Carre M, Barbier P; et al. (2006). “HIV-1 Tat protein enhances microtubule polymerization”. Retrovirology. 2: 5. doi:10.1186/1742-4690-2-5. PMID 15691386.
  • Giacca M (2006). “HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?”. Retrovirology. 2: 7. doi:10.1186/1742-4690-2-7. PMID 15698476.

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