
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Tabes Dorsalis history and symptoms
Introduction
Overview
Overview
A positive history of unprotected sexual activity or a proved treponemal infection in the setting of clinical manifestations is suggestive of tabes dorsalis. The most common symptoms of tabes dorsalis include lightning pains, impaired sensation and proprioception, hypesthesias, diminished reflexes or loss of reflexes, Poor coordination or loss of coordination, Unsteady gait (locomotor ataxia), sexual function problems and progressive sensory ataxia (inability to feel the lower limbs).
History and Symptoms
History and Symptoms
History
- Unprotected sexual activity
- HIV infection
- Immunocompromised state
- Immunosuppressive therapy
- Substance abuse
- Positive history of long-term untreated syphilis disease[1]
Common Symptoms
Common symptoms of tabes dorsalis include:
- Lightning pain[2]
- Impaired sensation and proprioception[3]
- Numbness[4]
- Inability to feel the lower limbs[5]
- Diminished reflexes or loss of reflexes[6]
- Poor coordination or loss of coordination[7]
- Unsteady gait (locomotor ataxia)[8]
- Sexual function problems[9]
Less Common Symptoms
Less common symptoms of tabes dorsalis include:
- Degeneration of the joints (Charcot joints)[10]
- Muscle weakness[11]
- Bladder control problems[12]
References
References
- β Kolar OJ, Burkhart JE (1977). “Neurosyphilis”. Br J Vener Dis. 53 (4): 221β5. PMCΒ 1045401. PMIDΒ 336144.
- β MAO S, LIU Z (2009). “Neurosyphilis manifesting as lightning pain”. Eur J Dermatol. 19 (5): 504β6. doi:10.1684/ejd.2009.0712. PMIDΒ 19487174.
- β Vora SK, Lyons RW (2004). “The medical Kipling–syphilis, tabes dorsalis, and Romberg’s test”. Emerg Infect Dis. 10 (6): 1160β2. doi:10.3201/eid1006.031117. PMCΒ 3323152. PMIDΒ 15224672.
- β Pandey S (2011). “Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis”. J Spinal Cord Med. 34 (6): 609β11. doi:10.1179/2045772311Y.0000000041. PMCΒ 3237288. PMIDΒ 22330117.
- β Sabre L, Braschinsky M, Taba P (2016). “Neurosyphilis as a great imitator: a case report”. BMC Res Notes. 9: 372. doi:10.1186/s13104-016-2176-2. PMCΒ 4964046. PMIDΒ 27465246.
- β Smikle MF, James OB, Prabhakar P (1988). “Diagnosis of neurosyphilis: a critical assessment of current methods”. South Med J. 81 (4): 452β4. PMIDΒ 3358168.
- β Mehrabian S, Raycheva M, Traykova M, Stankova T, Penev L, Grigorova O; et al. (2012). “Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging”. BMC Neurol. 12: 96. doi:10.1186/1471-2377-12-96. PMCΒ 3517431. PMIDΒ 22994551.
- β Gue JW, Wang SJ, Lin YY, Liao KK, Wong WW (1993). “Neurosyphilis presenting as tabes dorsalis in a HIV carrier”. Zhonghua Yi Xue Za Zhi (Taipei). 51 (5): 389β91. PMIDΒ 8334567.
- β Ahamed S, Varghese M, El Agib el N, Ganesa VS, Aysha M (2009). “Case of neurosyphilis presented as recurrent stroke”. Oman Med J. 24 (2): 134β6. doi:10.5001/omj.2009.29. PMCΒ 3273935. PMIDΒ 22334859.
- β Kaynak G, Birsel O, GΓΌven MF, OΔΓΌt T (2013). “An overview of the Charcot foot pathophysiology”. Diabet Foot Ankle. 4. doi:10.3402/dfa.v4i0.21117. PMCΒ 3733015. PMIDΒ 23919113.
- β Matijosaitis V, Vaitkus A, Pauza V, Valiukeviciene S, Gleizniene R (2006). “Neurosyphilis manifesting as spinal transverse myelitis”. Medicina (Kaunas). 42 (5): 401β5. PMIDΒ 16778468.
- β Wheeler JS, Culkin DJ, O’Hara RJ, Canning JR (1986). “Bladder dysfunction and neurosyphilis”. J Urol. 136 (4): 903β5. PMIDΒ 3761456.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
