Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Takayasu's arteritis medical therapy
Introduction
Overview
Overview
Pharmacologic medical therapy is recommended among patients with Takayasu’s arteritis to control inflammatory process and hypertension. Pharmacologic medical therapies for include corticosteroids, IL-6 receptor inhibitor, B-cell depletion agents, and cytotoxic drugs.
Medical Therapy
Medical Therapy
- Pharmacologic medical therapy is recommended among patients with Takayasu’s arteritis to control inflammatory process and hypertension.[1][2]
- Pharmacologic medical therapies for include corticosteroids, IL-6 receptor inhibitor, B-cell depletion agents, and cytotoxic drugs.
Takayasu’s arteritis
- 1 Corticosteroids
- Preferred regimen (1): prednisone 1 mg/kg PO qd (Consider osteoporosis prevention)
- 2 IL-6 receptor inhibitor
- Preferred regimen (1): Tocilizumab
- 3 B-cell depletion
- Preferred regimen (1): Rituximab
- 4 Cytotoxic agents
- Preferred regimen (1): methotrexate
- Preferred regimen (2): azathioprine
- Preferred regimen (3): cyclophosphamide
References
References
- ↑ Lupi-Herrera E, Sánchez-Torres G, Marcushamer J, Mispireta J, Horwitz S, Vela JE (January 1977). “Takayasu’s arteritis. Clinical study of 107 cases”. Am. Heart J. 93 (1): 94–103. PMID 12655.
- ↑ Keser G, Direskeneli H, Aksu K (May 2014). “Management of Takayasu arteritis: a systematic review”. Rheumatology (Oxford). 53 (5): 793–801. doi:10.1093/rheumatology/ket320. PMID 24097290.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]