Teratoma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Masoud Bitarafan, M.D[[3]]Amandeep Singh M.D.[4]

Overview

Teratomas are subtypes of germ cell tumors.Teratomas may be classified into four subgroups based on the histology and site features.

Classification

Teratomas may be classified into four subgroups based on the histology features.^[1]^[2]^[3]
- Mature teratoma which is benign cystic and solid.
- Immature teratoma which is malignant with some embryonic component.
- Malignant teratoma with some somatic malignant neoplasm component.
- Monodermal teratoma.
Teratomas may also be classified based on the site:^[4]
- Intragonadal (ovary and testis).
- Extragonadal (sacrococcygeal, retroperitoneum, mediastinum, and others).

References

↑ Zuquello RÁ, Tagliari G, Bagatini R, Camiña RH, Caron R, Lorencette NA; et al. (2016). “Immature teratoma presenting as a soft-tissue mass with no evidence of other sites of involvement: a case report”. Diagn Pathol. 11 (1): 76. doi:10.1186/s13000-016-0527-x. PMC 4986345. PMID 27528018.
↑ Peterson, Christine M.; Buckley, Celine; Holley, Susan; Menias, Christine O. (2012). “Teratomas: A Multimodality Review”. Current Problems in Diagnostic Radiology. 41 (6): 210–219. doi:10.1067/j.cpradiol.2012.02.001. ISSN 0363-0188.
↑ Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P; et al. (2016). “The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications”. Arch Gynecol Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
↑ Varma AV, Malpani G, Agrawal P, Malukani K, Dosi S (2017). “Clinicopathological spectrum of teratomas: An 8-year retrospective study from a tertiary care institute”. Indian J Cancer. 54 (3): 576–579. doi:10.4103/ijc.IJC_294_17. PMID 29798962.

Overview