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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Teratoma surgery

Introduction

Overview

Overview

Surgical intervention is the mainstay of treatment for teratoma.

Surgery

Surgery

  • Surgical intervention is the mainstay of treatment for mature teratoma and immature teratoma stage I in children.[1][2][3]
  • Observation after surgery is very important with serial of follow up exams and serum alpha fetoprotein.[4][5]
  • Surgery with fertility sparing and chemotherapy are indicated for immature teratoma stage II-IV in aldults.[6]
References

References

  1. ↑ Tapper D, Lack EE (1983). “Teratomas in infancy and childhood. A 54-year experience at the Children’s Hospital Medical Center”. Ann Surg. 198 (3): 398–410. doi:10.1097/00000658-198309000-00016. PMC 1353316. PMID 6684416.
  2. ↑ Göbel, U.; Schneider, D. T.; Calaminus, G.; Haas, R. J.; Schmidt, P.; Harms, D. (2000). “Germ-cell tumors in childhood and adolescence”. Annals of Oncology. 11 (3): 263–271. doi:10.1023/A:1008360523160. ISSN 0923-7534.
  3. ↑ Marina NM, Cushing B, Giller R, Cohen L, Lauer SJ, Ablin A; et al. (1999). “Complete surgical excision is effective treatment for children with immature teratomas with or without malignant elements: A Pediatric Oncology Group/Children’s Cancer Group Intergroup Study”. J Clin Oncol. 17 (7): 2137–43. doi:10.1200/JCO.1999.17.7.2137. PMID 10561269.
  4. ↑ Egler RA, Gosiengfiao Y, Russell H, Wickiser JE, Frazier AL (2017). “Is surgical resection and observation sufficient for stage I and II sacrococcygeal germ cell tumors? A case series and review”. Pediatr Blood Cancer. 64 (5). doi:10.1002/pbc.26311. PMID 27786428.
  5. ↑ Dharmarajan H, Rouillard-Bazinet N, Chandy BM (2018). “Mature and immature pediatric head and neck teratomas: A 15-year review at a large tertiary center”. Int J Pediatr Otorhinolaryngol. 105: 43–47. doi:10.1016/j.ijporl.2017.11.031. PMID 29447817.
  6. ↑ Norris HJ, Zirkin HJ, Benson WL (1976). “Immature (malignant) teratoma of the ovary: a clinical and pathologic study of 58 cases”. Cancer. 37 (5): 2359–72. doi:10.1002/1097-0142(197605)37:5<2359::aid-cncr2820370528>3.0.co;2-q. PMID 1260722.

Editor-In-Chief:
C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2]