Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Testicular cancer laboratory findings
Introduction
Overview
Overview
An elevated concentration of blood tumor marker tests is diagnostic of testicular cancer.
Laboratory Tests
Laboratory Tests
| Tumor type | Tumor markers | ||
|---|---|---|---|
| Human chorionic gonadotropin (HCG) | Alpha-fetoprotein (AFP) | Lactate dehydrogenase (LDH) | |
| Seminoma | ↑ | – | ↑ |
| Choriocarcinoma | ↑↑ | – | ↑ |
| Yolk sac tumor | – | ↑ | ↑ |
| Embryonal tumor | ↑ | ↑ | ↑ |
| Teratoma | – | ↑ | ↑ |
Sex cord stromal testicular tumor
Sex cord stromal testicular tumor
Leydig cell tumor[3]
Sertoli cell tumor[3]
- Estrogen is elevated
References
References
- ↑ Milose JC, Filson CP, Weizer AZ, Hafez KS, Montgomery JS (December 2011). “Role of biochemical markers in testicular cancer: diagnosis, staging, and surveillance”. Open Access J Urol. 4: 1–8. doi:10.2147/OAJU.S15063. PMC 3818947. PMID 24198649.
- ↑ Gilligan TD, Seidenfeld J, Basch EM, Einhorn LH, Fancher T, Smith DC, Stephenson AJ, Vaughn DJ, Cosby R, Hayes DF (July 2010). “American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors”. J. Clin. Oncol. 28 (20): 3388–404. doi:10.1200/JCO.2009.26.4481. PMID 20530278.
- ↑ 3.0 3.1 Al-Agha OM, Axiotis CA (February 2007). “An in-depth look at Leydig cell tumor of the testis”. Arch. Pathol. Lab. Med. 131 (2): 311–7. doi:10.1043/1543-2165(2007)131[311:AILALC]2.0.CO;2. PMID 17284120.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Shanshan Cen, M.D. [3]