Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Thin basement membrane disease history and symptoms
Introduction
Overview
Overview
Obtaining complete history both for the patient and family is an important aspect of diagnosing TBMD. The hallmark of TBMD is benign hematuria. A positive family history of incidental finding of intermittent or persistent hematuria is suggestive of TBMD. TBMD is mostly asymptomatic. Microscopic hematuria is found incidentally.
History and Symptoms
History and Symptoms
History
Obtaining complete medical and family history is an important aspect of diagnosing TBMD. It provides insight to cause and differentiation of TBMD with Alport syndrome, IgA nephropathy, Lupus Nephritis and other glomerulopathies. History may be obtained focusing specific areas including:
- Past medical history including URTI, Autoimmune Disease, Glomerulopathies.
- Positive family history of benign intermittent or persistent hematuria.
- Physical properties of urine (color, turbidity).
- Nature of micturation (frequency, dysuria)
- New onset hypertension or edema.
Symptoms
TBMD is mostly asymptomatic. The following signs are included:
- Intermiitent or persistent hematuria is found incidentally.
- New onset hypertension.
- Proteinuria.
- Renal impairment.
- Renal failure.
References
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]