Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Thrombotic thrombocytopenic purpura physical examination
Introduction
Overview
Overview
The presence of fever, purpura, petechiae, paleness in physical examination is highly suggestive of TTP.
Physical Examination
Physical Examination
Skin
- Bruising may be present even in mucous membrane called purpura
- Pinpoint dots on skin called petechiae
- Paleness
- Jaundice
Heart
- Dyspnea
- Arrhythmia
- Severe complications; sudden cardiac death, myocardial infarction, cardiogenic shock, heart failure
Neurologic
- No abnormalities
- Moderate signs [1]; speech changes, confusion
- Severe involvement: focal signs, seizure, stroke, coma
Renal
Other
Urine
- Dark urine
References
References
- ↑ Scully M, Yarranton H, Liesner R, Cavenagh J, Hunt B, Benjamin S; et al. (2008). “Regional UK TTP registry: correlation with laboratory ADAMTS 13 analysis and clinical features”. Br J Haematol. 142 (5): 819–26. doi:10.1111/j.1365-2141.2008.07276.x. PMID 18637802.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]