Thrombotic thrombocytopenic purpura screening
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Screening
Screening
- There is no insufficient evidence to recommend routine screening for TTP.[1]
- First test to be screening for ADAMTS13 activity. ADAMTS13 activity < 10%, TTP diagnosis is confirmed.
- In sever deficiency of ADAMTS13 second screening is detection of anti-ADAMTS13 IgG
- Gene sequencing of ADAMTS13 is a third test is used.
References
References
- ↑ Joly, Bérangère S.; Coppo, Paul; Veyradier, Agnès (2017). “Thrombotic thrombocytopenic purpura”. Blood. 129 (21): 2836–2846. doi:10.1182/blood-2016-10-709857. ISSN 0006-4971.
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