Thrombotic thrombocytopenic purpura surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

The mainstay of treatment for TTP is medical therapy. Surgery is usually reserved for patients with either no cure with plasma treatments and medicines.

Indications

Surgery is not the first line treatment option for patients withTTP when plasma treatments(PEX) and medicines do not cure TTP, surgery is needed.^[1]

Surgery

Surgery is not the first-line treatment option for patients withTTP. Sometimes splenectomy is needed, because the antibodies is made by cell in spleen that block ADAMTS13 enzyme activity.^[1]

References

↑ ^1.0 ^1.1 Medina PJ, Sipols JM, George JN (September 2001). “Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome”. Curr. Opin. Hematol. 8 (5): 286–93. PMID 11604563.

Overview