Thyroid adenoma laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Laboratory findings consistent with the diagnosis of thyroid adenoma include decreased thyroid stimulating hormone, elevated calcitonin, and decreased calcium.

Laboratory Findings

Blood or imaging tests may be done prior to or in lieu of a biopsy. The following blood tests are conducted:^[1]

Tests for serum thyroid autoantibodies are sometimes done to rule out autoimmune thyroid disease (which can mimic nodular disease).
Laboratory findings consistent with the diagnosis of multiple endocrine neoplasia type 2:
- Decreased thyroid stimulating hormone
- Antithyroid antibodies
- Elevated calcitonin
- Decreased calcium
- Antithyroid antibodies
- Serum calcitonin

Adapted from Arzu Tatlıpınar1 and İlkay Kartal [Updated 2015].The Evaluation of Thyroid Nodules. Journal of Thyroid Disorders & Therapy.2015.^[2]

Laboratory tests	Normal Range	Abnormal value
Serum
Thyroid stimulating hormone	0.4 – 4.0 milli-international units per liter	<0.4 or >4.0
Antithyroid antibodies	<35 IU/mL	>35 IU/mL
Serum calcitonin	less than 10pg/mL	>=100 pg/mL

References

↑ Bomeli SR, LeBeau SO, Ferris RL (April 2010). “Evaluation of a thyroid nodule”. Otolaryngol. Clin. North Am. 43 (2): 229–38, vii. doi:10.1016/j.otc.2010.01.002. PMC 2879398. PMID 20510711.
↑ İlkay Kartal, Arzu Tatlıpınar (2014). “The Evaluation of Thyroid Nodules”. Journal of Thyroid Disorders and Therapy. 04 (02). doi:10.4172/2167-7948.1000181. ISSN 2167-7948.