Tick-borne encephalitis is endemic to regions within Europe and Asia. These areas include territories spanning from France to Northern Japan; and from Russia to Albania. Incidence is approximately 5,000 to 13,000 infections per year. Vaccination is a method of preventing the virus, however the virus will still persist at 1 case per 10,000 unvaccinated individuals. The majority of infections occur between April and November with the highest rates of infection in the early and late summer periods. There is a higher incidence of infection among individuals above the age of 50.

• Located primarily in areas of Europe and Asia.
• From eastern France to Northern Japan, from northern Russia to Albania.
• European countries reporting tick-borne encephilitis infections include: Siberia, Baltic states, Albania, Austria, Belarus, Bosnia, Croatia, Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, Norway, Poland, Romania ,Serbia, Slovakia, Slovenia, Sweden, Switzerland, and Ukraine.
• Asian countries reporting tick-borne encephilitis infections include: China, Japan, Kazakhstan, Mongolia, and South Korea.^[1]

• 5,000 to 13,000 tick-borne encephilitis infections are reported each year.
• Overall risk for an unvaccinated individuals living within endemic regions is approximately 1 case per 10,000 people. ^[1]
• Russia and Europe report between 10-12,000 human cases annually.^[2]

• Majority of cases occur between April and November.
• Peak activity rates have been reported during early and late summer.^[1]

• Peak levels of incidence, as well as severity, are reported within individuals over the age of 50 years.^[1]