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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Tocofersolan

Introduction

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Overview

Overview

Tocofersolan (INN) or tocophersolan is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is polyethylene glycol derivative of α-tocopherol that enables water solubility.

Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease.[1] On 24 July 2009 the European Medicines Agency approved tocofersolan under the trade name Vedrop 50 mg/ml oral solution for the treatment of vitamin E deficiency due to digestive malabsorption in paediatric patients suffering from congenital or hereditary chronic cholestasis, from birth (in term newborns) to 16 or 18 years of age (depending on the region).[2]

Tocofersolan is also used in cosmetics and pharmaceuticals as an antioxidant.[3]

References

References

  1. ↑ “Tocophersolan Oral”. WebMD.
  2. ↑ “Vedrop Summary of Product Characteristics” (PDF). European Medicines Agency.
  3. ↑ Ash, Michael; Ash, Irene. Handbook of Preservatives. p. 568. ISBN 1-890595-66-7.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]