Toxic megacolon risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Overview
Common risk factors in the development of toxic negacolon include discontinuation of steroids, use of barium enemas, colonoscopy, chemotherapy, antidiarrheal drugs, anticholinergic drugs, narcotics, Severe chronic obstructive pulmonary disease, organ transplantation, cardiothoracic procedures, diabetes mellitus, immunosuppression, renal failure.
Risk Factors
Risk Factors
Common risk factors
- Common risk factors in the development of toxic megacolon include use of barium enema, colonoscopy, chemotherapy, antidiarrheal drugs, anticholinergic drug, narcotics, diabetes mellitus and immunosuppression.
- Common risk factors in the development of toxic megacolon include:[1][2][3][4][5]
Less Common Risk Factors
- Less common risk factors in the development of toxic megacolon include:[6][7]
- Organ transplantation
- Discontinuation of steroids
- Severe chronic obstructive pulmonary disease
- Renal failure
- Cardio-thoracic procedures
References
References
- ↑ “Toxic Megacolon: A Review for Emergency Department Clinicians – ScienceDirect”.
- ↑ Caprilli R, Vernia P, Colaneri O, Frieri G (1980). “Risk factors in toxic megacolon”. Dig. Dis. Sci. 25 (11): 817–22. PMID 6160025.
- ↑ Autenrieth DM, Baumgart DC (2012). “Toxic megacolon”. Inflamm. Bowel Dis. 18 (3): 584–91. doi:10.1002/ibd.21847. PMID 22009735.
- ↑ Sayedy, Leena (2010). “Toxic megacolon associatedClostridium difficilecolitis”. World Journal of Gastrointestinal Endoscopy. 2 (8): 293. doi:10.4253/wjge.v2.i8.293. ISSN 1948-5190.
- ↑ Earhart, Megan M. (2008). “The Identification and Treatment of Toxic Megacolon Secondary to Pseudomembranous Colitis”. Dimensions of Critical Care Nursing. 27 (6): 249–254. doi:10.1097/01.DCC.0000338869.70035.2b. ISSN 0730-4625.
- ↑ Velanovich V, LaPorta AJ, Garrett WL, Richards TB, Cornett PA (1992). “Pseudomembranous colitis leading to toxic megacolon associated with antineoplastic chemotherapy. Report of a case and review of the literature”. Dis. Colon Rectum. 35 (4): 369–72.
- ↑ Byrn JC, Maun DC, Gingold DS, Baril DT, Ozao JJ, Divino CM (2008). “Predictors of mortality after colectomy for fulminant Clostridium difficile colitis”. Arch Surg. 143 (2): 150–4, discussion 155. doi:10.1001/archsurg.2007.46. PMID 18283139.
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