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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Toxic multinodular goiter CT

Introduction

Overview

Overview

CT scan may be helpful in the diagnosis and fully characterizing the extent of substernal goitre. Findings on CT scan suggestive of multinodular goiter include enlarged and heterogeneous thyroid gland. CT scan is useful in defining the extent of tracheal deviation and compression. CT scan–guided fine needle aspiration biopsy(FNAB) may be helpful.

CT scan

CT scan

  • Neck CT scan may be helpful in the diagnosis and fully characterizing the extent of substernal or nonpalpable goitre.[1]
  • Findings on CT scan of neck suggestive of multinodular goiter include enlarged and heterogeneous thyroid gland.
  • CT scan is useful in defining the extent of tracheal deviation and compression.
  • Following CT scan with iodinated contrast, patients with underlying nontoxic multinodular goiter may develop thyrotoxicosis due to iodine load(Jod-Basedow effect).
  • CT scan–guided fine needle aspiration biopsy(FNAB) may be helpful in diagnosis of multinodular goiter.
  • PET scan with 18F-fluorodeoxyglucose can be done although it offers no additional diagnostic benefit in the evaluation of a thyroid nodule.[2]
Asymmetric multinodular enlargement of the thyroid gland with the right lobe larger than the left.Case courtesy of Dr Varun Babu, <a href=”https://radiopaedia.org/“>Radiopaedia.org</a>. From the case <a href=”https://radiopaedia.org/cases/55680“>rID: 55680</a>
References

References

  1. ↑ Hurley DL, Gharib H (1996). “Evaluation and management of multinodular goiter”. Otolaryngol. Clin. North Am. 29 (4): 527–40. PMID 8844728.
  2. ↑ Deandreis D, Al Ghuzlan A, Auperin A, Vielh P, Caillou B, Chami L, Lumbroso J, Travagli JP, Hartl D, Baudin E, Schlumberger M, Leboulleux S (2012). “Is (18)F-fluorodeoxyglucose-PET/CT useful for the presurgical characterization of thyroid nodules with indeterminate fine needle aspiration cytology?”. Thyroid. 22 (2): 165–72. doi:10.1089/thy.2011.0255. PMID 22257371.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]