Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Toxic multinodular goitre
Introduction
Overview
Overview
Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism – where there is excess production of thyroid hormones.
It is the second most common cause of hyperthyroidism after Graves disease.
Symptoms
Symptoms
Symptoms of toxic multinodular goitre are similar to that of hyperthyroidism, including:
- heat intolerance
- hyperkinesis
- tremor
- irritability
- weight loss
- increased appetite
- goitre (swelling of the thyroid gland)
- tachycardia (high heart rate – above 180 bpm at rest)
Related eponym
Related eponym
Plummer’s disease is named after an American physician Henry Stanley Plummer but refers to a single toxic nodule (adenoma) which may present with the background of a suppressed multinodular goitre.[1]
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753