Transferrin saturation

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Transferrin saturation, measured as a percentage, is a medical laboratory value. It is the ratio of serum iron and total iron-binding capacity, multiplied by 100. For an explanation of some clinical situations in which this ratio is important, see Total iron-binding capacity. The three results are usually reported together.

• Serum iron: 60-170 mcg/dl
• TIBC: 240-450 mcg/dl
• Transferrin saturation: 20-50%

mcg/dl = micrograms per deciliter.

Laboratories often use different units and “normal” may vary by population and the lab techniques used. Look at the individual laboratory reference values to interpret a specific test (for instance, your own).

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