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Transfusion-associated graft versus host disease primary prevention

Introduction

Overview

Overview

Primary Prevention

Primary Prevention

Prevention includes gamma irradiation of the lymphocyte-containing blood products. This procedure should be performed in transfusions when:

  • the recipient is immunocompromised
  • the blood components are from a family donor
  • HLA-matched platelets are transferred.

Another means of prevention is the use of third- or fourth-generation leukoreduction filters, although the efficacy of this procedure has not yet been documented.

References

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]