Transient erythroblastopenia of childhood
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood characterized by gradual onset of pallor.
Historical Perspective
Historical Perspective
Classification
Classification
Pathophysiology
Pathophysiology
Causes
Causes
The cause of TEC is unknown, but it has been suggested that an infection with Parvovirus B19 plays a role.
Differentiating Transient erythroblastopenia of childhood from Other Diseases
Differentiating Transient erythroblastopenia of childhood from Other Diseases
Epidemiology and Demographics
Epidemiology and Demographics
Risk Factors
Risk Factors
Screening
Screening
Natural History, Complications, and Prognosis
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Most patients recover completely within 1-2 months.
Diagnosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Individuals with TEC have a median age of presentation of 18-26 months; however, the disorder may occur in infants younger than 6 months and in children as old as age 10 years. Because of the gradual onset of the anemia, children are often healthier than expected from their low hemoglobin levels.
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Treatment
Medical Therapy
Surgery
Prevention
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