Transposition of the great vessels epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Kristin Feeney, B.S. [5]

Overview

The prevalence of TPA is approximately 47 per 100,000 individuals worldwide. TGA accounts for 5-7 percent of all congenital heart disease and 20 percent of cyanotic heart disease. There is no racial predilection to transposition of great vessels. Transposition of the great arteries has a 60-70% male predominance.

Epidemiology

Incidence

Transposition of the great arteries TGA is one of the commonest cyanotic congenital heart defects present in the first 24 hours of life.^[1]
The overall annual incidence of TGA is 20-30 per 100,000 live births.
TGA represents 5-7% of all congenital heart disease and 20% of cyanotic disease.

Demographics

Gender

Boys outnumber girls with an approximate ratio of 2:1.

Race

There is no racial predilection to transposition of great vessels.

References

↑ “Improved national prevalence estimates for 18 selected major birth defects–United States, 1999-2001”. MMWR Morb. Mortal. Wkly. Rep. 54 (51): 1301–5. January 2006. PMID 16397457.

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[pmid16397457-1] “Improved national prevalence estimates for 18 selected major birth defects–United States, 1999-2001”. MMWR Morb. Mortal. Wkly. Rep. 54 (51): 1301–5. January 2006. PMID 16397457.

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