
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions โ written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Transposition of the great vessels historical perspective
Introduction
Overview
Overview
The TGA was first described in 1797 by Matthew Baillie as a “singular malformation”. The word transposition was coined by Farre in 1814.
Historical Perspective
Historical Perspective
- The TGA was first described in 1797 by Matthew Baillie as a “singular malformation”.[1][2][3][4]
- In 1814 Farre described it as transposition.
- No treatment was available until the middle of the 20th century.
- In the 1950s, surgical atrial septectomy was developed followed by balloon atrial septostomy in the 1960s. These surgical therapies were not curative, but were palliative. They were later followed by physiological procedures.
- Today, the survival rate for infants with TGA is greater than 90%.
| Major Historical Events in TGA | ||
|---|---|---|
| Year | Author | Contribution |
| 1797 | Baillie | First morphological description of TGA |
| 1814 | Farre | First used the term TGA |
| 1948 | Hanlon and Blalock | Artirial septectomy |
| 1953 | Lilehei and Varco | Partial venous switch |
| 1955 | Thomas Baffes | Baffes operation |
| 1957 | Ake Senning | Atrial switch using atrial flaps |
| 1963 | Wiliam Mustard | Atrial switch using pericardium |
| 1966 | Rashkind and Miler | Introduced balloon atrial septostomy |
| 1975 | Jatene | Successful arterial switch |
| 1976 | Magdi Yocoub | Left ventricular training and arterial switch |
| 1981 | Lecompte | Lecompte maneuver |
| 1984 | Castenada | Neonatal arterial switch |
| 1989 | Jonas | Rapid two stage arterial swtich |
References
References
- โ Van Praagh R, Perez-Trevino C, Lรตpez-Cuellar M, Baker FW, Zuberbuhler JR, Quero M, Perez VM, Moreno F, Van Praagh S (December 1971). “Transposition of the great arteries with posterior aorta, anterior pulmonary artery, subpulmonary conus and fibrous continuity between aortic and atrioventricular valves”. Am. J. Cardiol. 28 (6): 621โ31. doi:10.1016/0002-9149(71)90049-x. PMIDย 5124722.
- โ Hanlon CR, Blalock A (March 1948). “Complete Transposition of the Aorta and the Pulmonary Artery: Experimental Observations on Venous Shunts as Corrective Procedures”. Ann. Surg. 127 (3): 385โ97. doi:10.1097/00000658-194803000-00001. PMCย 1513835. PMIDย 17859086.
- โ BLALOCK A, HANLON CR (January 1950). “The surgical treatment of complete transposition of the aorta and the pulmonary artery”. Surg Gynecol Obstet. 90 (1): 1โ15, illust. PMIDย 15396549.
- โ Weldon CS (April 1987). “The Blalock-Hanlon operation”. Ann. Thorac. Surg. 43 (4): 448โ9. doi:10.1016/s0003-4975(10)62834-2. PMIDย 3551863.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Kristin Feeney, B.S. [5]
