Trichoepithelioma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Trichoepithelioma is a neoplasm of the adnexa of the skin.^[1] Its appearance is similar to basal cell carcinoma.

One form has been mapped to chromosome 9p21.^[2]

Types

Trichoepitheliomas may be divided into the following types:^[3]^:672

Pathology

Trichoepitheliomas consisted of nests of basaloid cells. They lack the myxoid stroma and artefactual clefting seen in basal cell carcinoma. Mitoses are uncommon when compared to basal cell carcinoma.

Diagnosis

Physical Examination

Skin

Face

Trichoepithelioma. Adapted from Dermatology Atlas.^[4]
Trichoepithelioma. Adapted from Dermatology Atlas.^[4]
Trichoepithelioma. Adapted from Dermatology Atlas.^[4]
Trichoepithelioma. Adapted from Dermatology Atlas.^[4]
Trichoepithelioma. Adapted from Dermatology Atlas.^[4]

References

↑ “Trichoepithelioma: Overview – eMedicine Dermatology”. Retrieved 2009-02-11.
↑ Salhi A, Bornholdt D, Oeffner F; et al. (August 2004). “Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene”. Cancer Res. 64 (15): 5113–7. doi:10.1158/0008-5472.CAN-04-0307. PMID 15289313.
↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews’ Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 “Dermatology Atlas”.

[urlTrichoepithelioma:_Overview_-_eMedicine_Dermatology-1] “Trichoepithelioma: Overview – eMedicine Dermatology”. Retrieved 2009-02-11.

[pmid15289313-2] Salhi A, Bornholdt D, Oeffner F; et al. (August 2004). “Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene”. Cancer Res. 64 (15): 5113–7. doi:10.1158/0008-5472.CAN-04-0307. PMID 15289313.

[Andrews-3] James, William D.; Berger, Timothy G.; et al. (2006). Andrews’ Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

[Dermatology_Atlas-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 “Dermatology Atlas”.

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