Trigeminal neuralgia future or investigational therapies

Despite being treated medically as well as surgery, many patients of trigeminal neuralgia suffer not only from refractory pain but also from the side effects of medications and post surgical complications. This has increased the demand for more precise treatments which, along with pain relief, can also improve the quality of life. Emerging treatment options currently under clinical investigation are a novel sodium channel blocker (CNV1014802) that selectively blocks the Nav1.7 sodium channel, as well as local botulinum neurotoxin type A injections. Non-pharmacological options may include non-invasive electrical stimulation with transcranial direct current stimulation (tDCS), or repetitive transcranial magnetic stimulation (rTMS). All these things are currently under investigation and require further evaluation.^[1]

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