Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Tuberous sclerosis surgery
Introduction
Overview
Overview
Surgical options have been historically the only way to treat the TSC-associated complications, but with the introduction of the mTOR inhibitors they have been left for more severe or refractory complications.
Surgical Treatment
Surgical Treatment
Epilepsy
- Vagal nerve stimulation or surgical resection of CNS lesion responsible for the epilepsy may be used.[1]
Angiomyolipoma
- Treatment is done in a pre-emptive manner to prevent bleeding, reduce tumor size or slow its growth. Percutaneous embolization (which may present with postembolization syndrome) and nephron-sparing surgical resection are possible treatments.[1]
Subependymal Giant Cell Astrocytoma
- Surgical resection is the most performed treatment, but may complicate with incomplete resection, hemorrhage, infection and cerebrospinal fluid obstruction.[1]
Skin Lesions
For TSC-associated skin lesions, the following surgical treatments may be performed:
- Ablation with pulse laser dye or CO2;
- Surgery
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]