Tumor lysis syndrome laboratory findings

Laboratory findings consistent with the diagnosis of tumor lysis syndrome include high serum uric acid, potassium, phosphorus, and lactate dehydrogenase. Another laboratory abnormality is low calcium.^[1]

Laboratory findings consistent with the diagnosis of tumor lysis syndrome include:^[1][2]

• Blood:

• Hyperuricemia ≥ 476 μmol/l
• Hyperphosphatemia ≥ 2·1 mmol/l (children), x ≥1·45 mmol/l (adults)
• Hyperkalemia ≥ 6·0 mmol/l
• Hypocalcemia ≤ 1·75 mmol/l
• Creatinine ≥1.5 x ULN
• Lactate dehydrogenase > ULN
• Metabolic acidosis

• Urinalysis:

• Low urine output
• Uric acid crystals or amorphous urates
• High uric acid-creatinine ratio > 1.0

Template:WH Template:WS