Turner syndrome historical perspective

Turner syndrome was first described in 1938 by Henry Turner when he noticed a triad of short stature, cubitus valgus and pterygium colli. Other scientists went to to discover the pathophysiology of the45 XO karyotype and the presence of streaked ovaries.

• Turner syndrome was first described by Henry Turner, an Oklahoma endocrinologist in 1938 as a patient with short stature, sexual infantilism, cubitus valgus and pterygium colli. “Turner Syndrome – StatPearls – NCBI Bookshelf”.
• Ulrich (in 1930) and Bonnevie (in 1934) described similar findings in a young girl and mouse.
• Ovarian failure and streaked gonads were noted in 1944 by Henry Silver and Kaiser who found elevated gonadotrophins in a 32 month old child. “OVARIAN AGENESIS (CONGENITAL APLASTIC OVARIES) IN CHILDREN | JAMA Pediatrics | JAMA Network”.
• C.E Ford et al first described the pathophysiology of 45 XO in 1959 at Harwell, Oxfordshire and Guy’s Hospital in London.[2] It was found in a 14-year-old girl with signs of Turner syndrome. ^[1]

​

Template:WikiDoc Sources