
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Typhoid fever causes
Introduction

Overview
Overview
- Typhoid fever is caused by Salmonella enterica serotype Typhi (Salmonella Typhi).[1][2][3][4][5][6] Salmonella Typhi is a flagellated, facultatively anaerobic, gram negative bacillus that belongs to the Enterobacteriaceae family and contains three important antigens: O, H, and Vi.[7]
Causes
Causes
- Typhoid fever is caused by Salmonella enterica serotype Typhi (Salmonella Typhi).[1][2][3][4][5][8]
Serovars
Other Salmonellae which may cause similar symptoms include:
- Salmonella Paratyphi A
- Salmonella Paratyphi B
- Salmonella Paratyphi C
- Salmonella choleraesuis
Features of Salmonella Typhi[9][10][11]
- Gram negative bacillus
- Flagellated
- Facultatively anaerobic
- Three antigens O,H and Vi
- O polysaccharide antigen
- H flagellar antigen
- Vi outer capsular polysaccharide antigen
- Belongs to Enterobacteriaceae family
- Chemotroph
References
References
- β 1.0 1.1 Arndt MB, Mosites EM, Tian M, Forouzanfar MH, Mokhdad AH, Meller M; et al. (2014). “Estimating the burden of paratyphoid a in Asia and Africa”. PLoS Negl Trop Dis. 8 (6): e2925. doi:10.1371/journal.pntd.0002925. PMCΒ 4046978. PMIDΒ 24901439.
- β 2.0 2.1 Maskey AP, Day JN, Phung QT, Thwaites GE, Campbell JI, Zimmerman M; et al. (2006). “Salmonella enterica serovar Paratyphi A and S. enterica serovar Typhi cause indistinguishable clinical syndromes in Kathmandu, Nepal”. Clin Infect Dis. 42 (9): 1247β53. doi:10.1086/503033. PMIDΒ 16586383.
- β 3.0 3.1 Oboegbulam SI, Oguike JU, Gugnani HC (1995). “Microbiological studies on cases diagnosed as typhoid/enteric fever in south-east Nigeria”. J Commun Dis. 27 (2): 97β100. PMIDΒ 7499779.
- β 4.0 4.1 Vollaard AM, Ali S, Widjaja S, Asten HA, Visser LG, Surjadi C; et al. (2005). “Identification of typhoid fever and paratyphoid fever cases at presentation in outpatient clinics in Jakarta, Indonesia”. Trans R Soc Trop Med Hyg. 99 (6): 440β50. doi:10.1016/j.trstmh.2004.09.012. PMIDΒ 15837356.
- β 5.0 5.1 Wain J, Hendriksen RS, Mikoleit ML, Keddy KH, Ochiai RL (2015). “Typhoid fever”. Lancet. 385 (9973): 1136β45. PMIDΒ [//www.ncbi.nlm.nih.gov/pubmed/25458731
doi=10.1016/S0140-6736(13)62708-7 25458731
doi=10.1016/S0140-6736(13)62708-7] Check
|pmid=value (help). line feed character in|pmid=at position 9 (help) - β http://www.cdc.gov/typhoid-fever/health-professional.html
- β FΓ brega, Anna, and Jordi Vila. “Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation.” Clinical microbiology reviews 26.2 (2013): 308-341.
- β http://www.cdc.gov/typhoid-fever/health-professional.html
- β FΓ brega, Anna, and Jordi Vila. “Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation.” Clinical microbiology reviews 26.2 (2013): 308-341.
- β Grossman, Daniel A., et al. “Flagellar serotypes of Salmonella typhi in Indonesia: relationships among motility, invasiveness, and clinical illness.” Journal of Infectious Diseases 171.1 (1995): 212-216.
- β Schmoldt A, Benthe HF, Haberland G (1975). “Digitoxin metabolism by rat liver microsomes”. Biochem Pharmacol. 24 (17): 1639β41. PMIDΒ 10.1056/NEJMra020201 DOI: 10.1056/NEJMra020201 Check
|pmid=value (help).
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Aslam, M.B.B.S[2]
