Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
UBXN6
Introduction
UBX domain protein 6 is a protein in humans that is encoded by the UBXN6 gene.[1]
Further reading
Further reading
- Stapf C, Cartwright E, Bycroft M, Hofmann K, Buchberger A (November 2011). “The general definition of the p97/valosin-containing protein (VCP)-interacting motif (VIM) delineates a new family of p97 cofactors”. The Journal of Biological Chemistry. 286 (44): 38670–8. doi:10.1074/jbc.M111.274472. PMC 3207395. PMID 21896481.
- Nagahama M, Ohnishi M, Kawate Y, Matsui T, Miyake H, Yuasa K, Tani K, Tagaya M, Tsuji A (May 2009). “UBXD1 is a VCP-interacting protein that is involved in ER-associated degradation”. Biochemical and Biophysical Research Communications. 382 (2): 303–8. doi:10.1016/j.bbrc.2009.03.012. PMID 19275885.
- Falsone SF, Gesslbauer B, Rek A, Kungl AJ (July 2007). “A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome”. Proteomics. 7 (14): 2375–83. doi:10.1002/pmic.200600996. PMID 17623298.
- Ritz D, Vuk M, Kirchner P, Bug M, Schütz S, Hayer A, Bremer S, Lusk C, Baloh RH, Lee H, Glatter T, Gstaiger M, Aebersold R, Weihl CC, Meyer H (August 2011). “Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations”. Nature Cell Biology. 13 (9): 1116–23. doi:10.1038/ncb2301. PMC 3246400. PMID 21822278.
- Madsen L, Andersen KM, Prag S, Moos T, Semple CA, Seeger M, Hartmann-Petersen R (2008). “Ubxd1 is a novel co-factor of the human p97 ATPase”. The International Journal of Biochemistry & Cell Biology. 40 (12): 2927–42. doi:10.1016/j.biocel.2008.06.008. PMID 18656546.
- Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ (September 2008). “UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover”. Cell. 134 (5): 804–16. doi:10.1016/j.cell.2008.06.048. PMC 2614663. PMID 18775313.
- Kern M, Fernandez-Sáiz V, Schäfer Z, Buchberger A (March 2009). “UBXD1 binds p97 through two independent binding sites”. Biochemical and Biophysical Research Communications. 380 (2): 303–7. doi:10.1016/j.bbrc.2009.01.076. PMID 19174149.
- Carim-Todd L, Escarceller M, Estivill X, Sumoy L (January 2001). “Identification and characterization of UBXD1, a novel UBX domain-containing gene on human chromosome 19p13, and its mouse ortholog”. Biochimica et Biophysica Acta. 1517 (2): 298–301. doi:10.1016/s0167-4781(00)00248-7. PMID 11342112.