Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Ureteropelvic junction obstruction causes
Introduction
Overview
Overview
Causes
Causes
UPJ obstruction generally occurs when a baby is still growing in the womb. This is called a congenital condition (present from birth). Most of the time, the blockage is caused when the connection between the ureter and the renal pelvis narrows. This causes urine to build up, damaging the kidney.
The condition can also be caused when a blood vessel is located in the wrong position over the ureter. In older children and adults, UPJ obstruction can be due to scar tissue, infection, previous treatments for a blockage, or kidney stones.
UPJ obstruction is the most frequently diagnosed cause of urinary obstruction in children. It is now commonly diagnosed during prenatal ultrasound studies. In some cases, the condition isn’t seen until after birth. Children may have an abdominal mass or a urinary tract infection
The most severe cases of UPJ obstruction may require surgery early in life. However, the majority of cases may not require surgery until later in life, and some cases do not require surgery at all.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]