Urethral cancer classification

Urethral cancer may be classified based on histology into 3 sub types which include transitional cell carcinoma, squamous cell carcinoma, and adenocarcinoma. It may also be classified based on anatomical location of cancer into distal urethral cancer, proximal urethral cancer.

Urethral cancer can be classified based on histology into:

• Transitional cell (55%)
• Squamous cell (21.5%)
• Adenocarcinoma (16.4%)
• Melanoma

Urethral cancer can also be classified based on anatomical location into:

• Distal Urethral Cancer: ^[1]
  • Female: Distal third of the urethra
  • Males: Anterior, or penile portion of the urethra
• Proximal Urethral Cancer:
  • Females: Not limited to distal third
  • Male: Bulbomembranous and prostatic urethra