Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Urethral cancer historical perspective
Introduction
Overview
Overview
Adenocarcinoma of the urethra in females, a rare malignancy was discovered as early as 1945. Case reports of primary urethral cancers in males have been reported as early as 1948.
Historical perspective
Historical perspective
- In 1945, adenocarcinoma of the urethra was first discovered and described in females.[1]
- Later in 1948, carcinoma of urethra in males is disovered.[2]
- In 1962, a case of melanosarcoma of urethra is described.[3]
- A case of rhabdomyosarcoma in a 5 year old girl has been described in the year 2007.[4]
- Carcinoma insitu in bladder and urethra among renal transplant patient has been reported in the year 2008.[5]
Land mark events
Land mark events
- FDA approved the first chemotherapy drug “cisplatin” for treatment of bladder tumors in 1978 and the drug is also being used for the treatment of urethral cancers..
- FDA approved the use of live bacterium, bacillus Calmette-Guérin (BCG) for treatment and prevent the recurrence of superficial tumors in 1990.[7]
- New chemotherapy combination regimen including gemcitabine with cisplatin is introduced as more effective with less side effects compare to MVAC therapy in 2000.[8]
- Photodynamic therapy is an innovative therapeutic modality in urologic malignancy.[9]
References
References
- ↑ Feltes Ochoa JA, Blanco Carballo O, Sánchez Angel T, Villacampa Aubá F, Conde Gallego E (September 2005). “[Adenocarcinoma of the female urethra: report of two cases and bibliography review]”. Arch. Esp. Urol. (in Spanish; Castilian). 58 (7): 677–82. PMID 16294793.
- ↑ FEVES LJ, BROUN JR (February 1948). “Primary carcinoma of the male urethra; case report”. Northwest Med. 47 (2): 122. PMID 18857371.
- ↑ SIGNORELLI H (April 1962). “[Primary tumors of the male urethra. (Apropos of a case of melanosarcoma of the urethra)]”. Presse Med (in French). 70: 1038–40. PMID 13912737.
- ↑ Liu AX, Zhou JH, Jin HM, Zhu CK, Cheng XD (June 2007). “Primary rhabdomyosarcoma of urethra in a 5-year-old girl: case report and literature review”. Urology. 69 (6): 1208.e17–9. doi:10.1016/j.urology.2007.03.022. PMID 17572220.
- ↑ Tillou X, Raynal G, Limani K, Saint F, Petit J (December 2008). “[Carcinoma in situ in bladder and urethra among renal transplanted patient: failure of BCG therapy]”. Prog. Urol. (in French). 18 (13): 1097–9. doi:10.1016/j.purol.2008.08.002. PMID 19041819.
- ↑ SARGENT JW (1956). “Total urethrectomy for carcinoma of the female urethra”. Postgrad Semin Am Urol Assoc North Cent: 79–83. PMID 13567645.
- ↑ Askeland EJ, Newton MR, O’Donnell MA, Luo Y (2012). “Bladder Cancer Immunotherapy: BCG and Beyond”. Adv Urol. 2012: 181987. doi:10.1155/2012/181987. PMC 3388311. PMID 22778725.
- ↑ Als AB, Sengelov L, Von Der Maase H (2008). “Gemcitabine and cisplatin in locally advanced and metastatic bladder cancer; 3- or 4-week schedule?”. Acta Oncol. 47 (1): 110–9. doi:10.1080/02841860701499382. PMID 17851853.
- ↑ Colin P, Estevez JP, Betrouni N, Nevoux P, Puech P, Leroy X, Biserte J, Villers A, Mordon S (July 2011). “[Photodynamic therapy and urothelial carcinoma]”. Bull Cancer (in French). 98 (7): 769–78. doi:10.1684/bdc.2011.1389. PMID 21708516.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]