Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
VIPoma natural history, complications and prognosis
Introduction
Overview
Overview
If left untreated, patients with VIPoma may progress to develop watery diarrhea, abdominal pain, bloating, nausea, vomiting, skin rash, backache, flushing, and lethargy. Common complications of VIPoma include metastasis, cardiac arrest from low blood potassium level, and dehydration. The presence of metastasis is associated with a particularly poor prognosis among patients with VIPoma, with a 5 year survival rate of 60%.
Natural History
Natural History
- If left untreated, patients with VIPoma may progress to develop watery diarrhea, abdominal pain, bloating, nausea, vomiting, skin rash, backache, flushing, and lethargy.[1]
- VIPoma have a very slow growth rate compared to the most malignant tumors.
Complications
Complications
Common complications of VIPoma include:[2][3]
- Metastasis
- Cardiac arrest from low blood potassium level
- Dehydration
Prognosis
Prognosis
References
References
- ↑ Natanzi, Naveed; Amini, Mazyar; Yamini, David; Nielsen, Shawn; Ram, Ramin (2009). “Vasoactive Intestinal Peptide Tumor”. Scholarly Research Exchange. 2009: 1–7. doi:10.3814/2009/938325. ISSN 1687-8299.
- ↑ J. V. VERNER & A. B. MORRISON (1958). “Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia”. The American journal of medicine. 25 (3): 374–380. doi:10.1016/0002-9343(58)90075-5. PMID 13571250. Unknown parameter
|month=ignored (help) - ↑ A. Ayub, M. Zafar, A. Abdulkareem, M. A. Ali, T. Lingawi & A. Harbi (1993). “Primary hepatic vipoma”. The American journal of gastroenterology. 88 (6): 958–961. PMID 8389095. Unknown parameter
|month=ignored (help) - ↑ Nilubol N, Freedman EM, Quezado MM, Patel D, Kebebew E (2016). “Pancreatic Neuroendocrine Tumor Secreting Vasoactive Intestinal Peptide and Dopamine With Pulmonary Emboli: A Case Report”. J Clin Endocrinol Metab. 101 (10): 3564–3567. doi:10.1210/jc.2016-2051. PMC 5052354. PMID 27583474.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]Parminder Dhingra, M.D. [3] Homa Najafi, M.D.[4]