Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Ventricular septal defect causes
Introduction
Overview
Overview
The causes of VSD are not fully known. The septal defect between the right and left ventricle can be congenital that occurs alone or with other congenital abnormalities. Genetic association suggests the involvement of chromosome band 22q11 microdeletion in the mechanism of VSD development. In adults, Heart attacks can be complicated by the development of VSD.
Causes
Causes
- The causes of VSD are not yet known. This defect often occurs along with other congenital heart defects[1]
- In adults, ventricular septal defects are a rare but serious complication of heart attacks. These holes are related to heart attacks and do not result from a birth defect.
- Genetics – The frequent association between arch abnormalities and significant conal VSDs suggests a common mechanism involving a chromosome band 22q11 microdeletion. Deletions in this area have not been linked with isolated supracristal VSDs.
- Maternal Drug use – Clomifene
References
References
- ↑ Spicer DE, Hsu HH, Co-Vu J, Anderson RH, Fricker FJ (2014). “Ventricular septal defect”. Orphanet J Rare Dis. 9: 144. doi:10.1186/s13023-014-0144-2. PMC 4316658. PMID 25523232.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Leida Perez, M.D. Associate Editor(s)-In-Chief: Keri Shafer, M.D. [2], Atif Mohammad, M.D., Priyamvada Singh, MBBS