Ventricular septal defect causes

The causes of VSD are not fully known. The septal defect between the right and left ventricle can be congenital that occurs alone or with other congenital abnormalities. Genetic association suggests the involvement of chromosome band 22q11 microdeletion in the mechanism of VSD development. In adults, Heart attacks can be complicated by the development of VSD.

• The causes of VSD are not yet known. This defect often occurs along with other congenital heart defects^[1]

• In adults, ventricular septal defects are a rare but serious complication of heart attacks. These holes are related to heart attacks and do not result from a birth defect.

• Genetics – The frequent association between arch abnormalities and significant conal VSDs suggests a common mechanism involving a chromosome band 22q11 microdeletion. Deletions in this area have not been linked with isolated supracristal VSDs.

• Maternal Drug use – Clomifene

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