Meningitis was first discovered by Hippocrates. Wallgren described aseptic meningitis in 1924 and defined it as a disease with acute onset that has typical systematic symptoms of meningeal involvement, in association with a cerebrospinal fluid (CSF) typical of meningitis (typically with a mononuclear cell predominance). Additionally, there was absence of bacteria on stain and culture and there was no identifiable parameningeal infection.^[1]

• Meningitis was described first by the hippocrates, but it was first accurately identified by the Swiss Vieusseux (a scientific-literary association) during an outbreak in Geneva, Switzerland in 1805.^[2]
• In 1661, Thomas Willis first described the inflammation of meninges and an epidemic of meningitis.
• In 1891, Heinrich Quincke provided an early analysis of CSF by introducing a new technique of lumbar puncture.
• In early 19th century, detailed profile of CSF analysis in meningitis was explained by William Mestrezat, and H. Houston Merritt.
• Wallgren first described aseptic meningitis was in 1924.