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Von Braun reaction
Introduction
The Von Braun reaction is an organic reaction in which a tertiary amine reacts with cyanogen bromide to an organocyanamide [1]. An example is the reaction of dimethyl-α-naphthylamine [2]:
The reaction mechanism consists of two nucleophilic substitutions: the amine is the first nucleophile displacing the bromine atom which then acts as the second nucleophile [3].
References
References
- ↑ Von Braun, Heider, and Muller, Ber., 51, 281 (1918).
- ↑ Organic Syntheses, Coll. Vol. 3, p.608 (1955); Vol. 27, p.56 (1947). http://www.orgsynth.org/orgsyn/pdfs/CV3P0608.pdf
- ↑ Template:JerryMarch