Von Willebrand disease risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2] Nazia Fuad M.D.

Overview

There are no established risk factors for Von Willebrand disease however, individual’s ABO blood group can influence presentation and pathology of vWD. Those individuals with blood group O have a lower mean level than individuals with other blood groups. Common risk factors in the development of Von Willebrand disease include positive family history and consanguineous relationships. Less common risk factors in the development of Von Willebrand disease include lymphoproliferative disorders and aortic stenosis.

Risk factors

Common Risk Factors

Common risk factors in the development of Von Willebrand disease include:^[1]
- Positive family history
- Consanguineous relationships

Less Common Risk Factors

Less common risk factors in the development of Von Willebrand disease include:^[1]

References

↑ ^1.0 ^1.1 Ng CJ, Di Paola J (June 2018). “von Willebrand Disease: Diagnostic Strategies and Treatment Options”. Pediatr. Clin. North Am. 65 (3): 527–541. doi:10.1016/j.pcl.2018.02.004. PMID 29803281.

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[pmid29803281-1] 1.0 ^1.1 Ng CJ, Di Paola J (June 2018). “von Willebrand Disease: Diagnostic Strategies and Treatment Options”. Pediatr. Clin. North Am. 65 (3): 527–541. doi:10.1016/j.pcl.2018.02.004. PMID 29803281.

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