Wild-type (senile) amyloidosis physical examination

Physical examination of patients with wild-type (senile) amyloidosis can be significant for the condition in question and can also translate the variety of pathologies as a part of aging and age-related comorbidities.

Physical examination of patients with wild-type (senile) amyloidosis can be significant for the condition in question and can also translate the variety of pathologies as a part of aging and age-related comorbidities.

• Patients with wild-type (senile) amyloidosis appear senile.
• Exact appearance of the patients depend upon the severity of the condition.

• Hypertension
• Tachycardia

• Edema

• HEENT examination of patients with wild-type (senile) amyloidosis is usually normal.

• Elevated jugular pressure^[1]

• Pulmonary examination of patients with wild-type (senile) amyloidosis is usually normal.

• Third heart sound
• Fourth heart sound
• Arrhythmias ^[2]
• Auscultation may also reveal rales, heart murmurs, and/or other pathologic heart sounds.
• In patients with valvular heart disease involvement, murmurs of mitral and tricuspid regurgitation may be heard.

• Hepatomegaly may be present in the setting of right heart failure
• Ascites may be present in the setting of right heart failure
• Splenomegaly is rare

• Back examination of patients with wild-type (senile) amyloidosis is usually normal.

• Genitourinary examination of patients with wild-type (senile) amyloidosis is usually normal.

• Peripheral neuropathy

• Peripheral edema^[3]