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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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ZC3H12A

Introduction

Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.[1]

ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.

References

References

  1. ↑ “Entrez Gene: Zinc finger CCCH-type containing 12A”.
Further reading

Further reading

  • Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE, Fu M (2008). “A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages”. The Journal of Biological Chemistry. 283 (10): 6337–46. doi:10.1074/jbc.M707861200. PMID 18178554.