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Zollinger-Ellison syndrome causes

Introduction

Overview

Overview

The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 (MEN1).

Causes

Causes

  • Hypergastrinemia (an increased fasting serum gastrin level) is the hallmark of ZES. [2]
  • Causes of Hypergastrinemia: [2]
Causes of Hypergastrinemia
Appropriate Hypergastrinemia
Inappropriate Hypergastrinemia
Spurious hypergastrinemia
  • Inaccurate assay
  • Nonfasting patient
References

References

  1. ↑ National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes
  2. ↑ 2.0 2.1 Metz DC (2012). “Diagnosis of the Zollinger–Ellison syndrome”. Clin. Gastroenterol. Hepatol. 10 (2): 126–30. doi:10.1016/j.cgh.2011.07.012. PMID 21806955.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2] Mohamad Alkateb, MBBCh [3]