Follicular lymphoma laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Laboratory tests for follicular lymphoma include complete blood count (CBC), blood chemistry studies, bone marrow biopsy and aspiration, lymph node biopsy, cytogenetics studies, flow cytometry, immunohistochemistry, FISH, genetic testing, and immunophenotyping.

Laboratory tests for follicular lymphoma include the following

• Complete blood count (CBC)
• Complete metabolic panel
• HBV, HCV and HIV testing
• Serum LDH levels and serum β₂-microglobulin levels.
• Bone marrow biopsy and aspiration
• Lymph node biopsy
• Chest x ray and abdominal ultrasound
• CT scan
• PET scan
• Cytogenetics studies
• Flow cytometry
• Immunohistochemistry
• FISH
• Genetic testing
• Immunophenotyping: BCL-2+, BCL6+, CD5-, CD10+, CD19, CD20, CD22, CD43, CD79a, heavy and light chains rearranged, t(14;18)(q32:q21)-85% with rearrangement of BCL-2 gene.
• Endoscopy for gastrointestinal lymphoma