Gonadoblastoma risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
The most potent risk factor in the development of gonadoblastoma is gonadal dysgenesis. The risk also increases with age.
Risk Factors
- The most potent risk factor in the development of gonadoblastoma is gonadal dysgenesis.[1][2]
- The risk of gonadoblastoma development increases with age. In individuals with XY gonadal abnormalities, it reaches up to 30% by the age of thirty years.
- Other risk factors include patients with Turner syndrome and having Y chromosome contents.
References
- ↑ Esin, Sertac; Baser, Eralp; Kucukozkan, Tuncay; Magden, Hasim Ata (2011). “Ovarian gonadoblastoma with dysgerminoma in a 15-year-old girl with 46, XX karyotype: case report and review of the literature”. Archives of Gynecology and Obstetrics. 285 (2): 447–451. doi:10.1007/s00404-011-2073-9. ISSN 0932-0067.
- ↑ Sperling, M (2014). Pediatric endocrinology. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-4858-7.
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