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Plummer-Vinson syndrome risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

There are no established risk factors for Plummer-Vinson syndrome. However, chronic irritation of the esophagus may predispose to an increased frequency of esophageal webs or strictures. Conditions which can irritate esophagus includes thermal injury, mechanical injury, achalasia, esophageal diverticulum, chronic lye stricture, radiation therapy, injection sclerotherapy, gastric resection, celiac disease, tylosis and scleroderma.

Risk Factors

There are no established risk factors for Plummer-Vinson syndrome. However, chronic irritation of the esophagus may predispose to an increased frequency of esophageal webs or strictures. Conditions which can irritate esophagus includes:[1][2]

References

  1. Novacek G (2006). “Plummer-Vinson syndrome”. Orphanet J Rare Dis. 1: 36. doi:10.1186/1750-1172-1-36. PMC 1586011. PMID 16978405.
  2. Zimmer V, Buecker A, Lammert F (2009). “Sideropenic dysphagia”. Gastroenterology. 137 (6): e1–2. doi:10.1053/j.gastro.2009.03.051. PMID 19879220.

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