Normoblast

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

An erythroblast is a type of red blood cell which still retains a cell nucleus. It is the immediate precursor of a normal erythrocyte.

The term normoblast is sometimes used as a synonym for erythroblast, but at other times it is considered a subcategory. In the latter context, there are two types of erythroblasts:

• “normoblasts” – develop as expected
• “megaloblasts” – an unusually large erythroblast that can be associated with pernicious anemia and folic acid deficiency (collectively called megaloblastic anemia)

There are four stages in the development of a normoblast.

Image	Description
	Pronormoblast
	Basophilic normoblast
	Polychromatic normoblast (also polychromatophilic)
	Orthochromatic normoblast (also orthochromatophilic)

• 
  Blood cell lineage
• 
  Hematopoiesis
• 
  Blood: Schistocytes: Micro blood film shows an excellent example with normoblast.

• Erythropoiesis
• Hemopoiesis
• Pluripotential hemopoietic stem cell

• Pronormoblasts Presented by the University of Virginia
• Basophilic Normoblasts Presented by the University of Virginia
• Polychromatophilic Normoblasts Presented by the University of Virginia
• Orthochromatic Normoblasts Presented by the University of Virginia
• Template:Dorlands – “normoblast”
• Template:Dorlands – “erythroblast”
• Template:EMedicineDictionary
• Normoblasts at the US National Library of Medicine Medical Subject Headings (MeSH)
• Histology image: 01804loa – Histology Learning System at Boston University – “Bone Marrow and Hemopoiesis bone marrow smear, erythroblast series with proerythroblast “
• Histology at uiowa.edu

Template:Blood id:Prorubrisit

Template:WikiDoc Sources