Unstable angina non ST elevation myocardial infarction

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.; Smita Kohli, M.D.; Neil Gheewala, M.D. [3]; Bryan Piccirillo, B.S., M.D.

Synonyms and keywords: Angina at rest; rest angina; progressive angina; crescendo angina; accelerating angina; new-onset angina; pre-infarction angina; unstable angina pectoris; UAP; UA; new-onset angina; angina – unstable

Unstable Angina | Non-ST Elevation Myocardial Infarction

Women | Diabetic Patients | Post CABG Patients | Elderly | Chronic Kidney Disease | Substance Abusers | Prinzmetal’s Angina | Cardiovascular Syndrome X

History and Symptoms | Physical Examination | Blood Studies | Biomarkers | Electrocardiogram | Chest X Ray | Echocardiography | Coronary Angiography

Primary Prevention

Immediate Management: Overview | Oxygen | Nitrates | Analgesics | Beta Blockers | Calcium Channel Blocker | Renin-Angiotensin-Aldosterone Inhibitors

Antithrombin Therapy: Overview | Unfractionated Heparin | Low Molecular Weight Heparin | Direct Thrombin Inhibitors | Factor Xa Inhibitors | Long Term Anticoagulation

Antiplatelet Agents: Antiplatelet Therapy Recommendations | Aspirin | Thienopyridines | Glycoprotein IIb/IIIa Inhibitor | Additional Management Considerations

Mechanical Reperfusion: Initial Conservative Versus Initial Invasive Strategies | PCI | CABG

Complications of Bleeding and Transfusion: Overview | Incidence | Definitions | Predictors and Causes of Bleeding | Blood Transfusions | Prognosis | Prevention | Recommendations

Discharge Care: Medical Regimen | Post-Discharge Follow-Up | Cardiac Rehabilitation

Long-Term Medical Therapy and Secondary Prevention: Overview | Convalescent and Long-Term Antiplatelet Therapy | Beta Blockers | Inhibition Of The Renin-Angiotensin-Aldosterone System | Nitroglycerin Therapy | Calcium Channel Blockers | Warfarin Therapy | Lipid Management | Blood Pressure Control | Smoking Cessation | Weight Management | Physical Activity | Patient Education | Influenza | Depression | Nonsteroidal Anti-Inflammatory Drugs | Hormone Therapy | Antioxidant Vitamins and Folic Acid | Quality Care and Outcomes

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Unstable angina is considered an absolute contraindication to the use of the following medications:

• Dalteparin
• Fingolimod
• Levothyroxine

Case #1

• Acute Coronary Syndrome Risk Stratification
• Chronic stable angina
• Non ST Elevation Myocardial Infarction
• ST Elevation Myocardial Infarction
• Coronary Heart Disease
• PCI

• Clinical Trial Results: An up to date resource of Cardiovascular Research
• Risk Assessment Tool for Estimating Your 10-year Risk of Having a Heart Attack – based on information of the Framingham Heart Study, from the United States National Heart, Lung and Blood Institute

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