Junctional tachycardia
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Accelerated junctional rhythm; focal junctional tachycardia; automatic junctional tachycardia; His-bundle tachycardia; ectopic junctional tachycardia; junctional ectopic rhythm.
Overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Junctional tachycardia is a narrow complex supraventricular tachycardia characterized by electrical impulse generation from theAV node that is independent of or dissociated from that of the sinoatrial node (SA node) at a rate > 60 beats per minute.
References
Historical Perspective
Classification
Pathophysiology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Normally, the atrioventricular node (AVN) can generate an escape rhythm of 40-60 beats per minute in case the sinoatrial node(SA node) or atrial pacemakers fail (sinus arrest) or slow (sinus bradycardia) or if there is complete heart block. Thisjunctional escape rhythm generates a normal, narrow QRS complex rhythm at a rte below 60 beats per minute (junctional bradycardia) as the electrical impulses once they are generated are conducted with normal velocity down the His-Purkinje system. Retrograde P waves (i.e. upside down) due to retrograde or backward conduction may or may not be present in junctional bradycardia.
In contrast to a junctional escape rhythm or junctional bradycardia at a rate of 40-60 beats per minute, junctional tachycardia is faster, at a rate > 60 beats per minute. Junctional tachycardia generates a normal, narrow QRS complex rhythm as the electrical impulses are conducted with normal velocity down the His-Purkinje system. Retrograde P waves (i.e. upside down) P waves due to retrograde or backward conduction may or may not be present.
The cause of the more rapid firing of the atrioventricular node is thought to be due to enhanced automaticity as a result of abnormal Calcium metabolism in the sarcoplastic reticulum.[1]
References
- ↑ Kim D, Shinohara T, Joung B, Maruyama M, Choi EK, On YK. Calcium dynamics and the mechanisms of atrioventricular junctional rhythm. J Am Coll Cardiol. Aug 31 2010;56(10):805-12.
Causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayokunle Olubaniyi, M.B,B.S [2]
Overview
Junctional tachycardia may oocur either as a result of enhanced automaticity of the AV node when the SA node is bradycardic or discharges at a slower rate than the AV node (e.g. myocardial infarction, digitalis toxicity) or when an ectopic focus with an abnormal automaticity develops within or adjacent to the AV junction. Other causes include: hypoxia, electrolyte imbalance, and infections such as rheumatic fever, Lyme disease.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Beta blockers
- Cardiac surgery
- Digitalis toxicity
- Hypokalemia
- Hypothermia
- Hypoxia
- Myocardial infarction
- Pericarditis
Causes by Organ System
| Cardiovascular | Cardiac surgery, LQT type 4, myocardial infarction, pericarditis, Wolff-Parkinson-White syndrome |
| Chemical/Poisoning | Grayanotoxin |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Amiodarone, beta blockers, cimetidine, clonidine, diltiazem, flumazenil, guanethidine, isoproterenol infusion, lithium, methyldopa, reserpine, verapamil |
| Ear Nose Throat | No underlying causes |
| Endocrine | Hemochromatosis, hypothyroidism |
| Environmental | Hypothermia |
| Gastroenterologic | No underlying causes |
| Genetic | Emery-Dreifuss muscular dystrophy, LQT type 4, muscular dystrophy, Wolff-Parkinson-White syndrome |
| Hematologic | No underlying causes |
| Iatrogenic | Cardiac surgery |
| Infectious Disease | Chagas disease, diphtheria, leptospirosis, Lyme disease, rheumatic fever, salmonella typhosa, trichinosis |
| Musculoskeletal/Orthopedic | Emery-Dreifuss muscular dystrophy, muscular dystrophy |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | Hypokalemia, hypothermia |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | Beta blockers, carbamazepine poisoning, digitalis toxicity, lithium |
| Psychiatric | No underlying causes |
| Pulmonary | Hypoxia |
| Renal/Electrolyte | Hypokalemia |
| Rheumatology/Immunology/Allergy | Amyloidosis, scleroderma |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Junctional tachycardia causes developed by WikiDoc.org
Causes in Alphabetical Order
References
Differentiating Junctional tachycardia from other Diseases
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiation of Junctional Tachycardia from other Tachycardias
- Sinus tachycardia:
- Atrioventricular nodal reentrant tachycardia: It can appear similar to atrioventricular nodal reentrant tachycardia.[1]
One form is junctional ectopic tachycardia.
References
- ↑ Srivathsan K, Gami AS, Barrett R, Monahan K, Packer DL, Asirvatham SJ (2008). “Differentiating atrioventricular nodal reentrant tachycardia from junctional tachycardia: novel application of the delta H-A interval”. J. Cardiovasc. Electrophysiol. 19 (1): 1–6. doi:10.1111/j.1540-8167.2007.00961.x. PMID 17916156. Unknown parameter
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Epidemiology and Demographics
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
Sex
Males and females are affected equally.
References
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Surgery | Primary Prevention |Secondary Prevention | Cost-Effectiveness of Therapy |Future or Investigational Therapies
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