Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Acute tubular necrosis primary prevention
Introduction
Overview
Overview
Effective measures for the primary prevention of acute tubular necrosis include identification of individuals who are at high risk and prompt treatment for underlying conditions, maintain volume status and adequate renal perfusion by proper hydration or isotonic fluid administration, monitoring fluid input and urine output, serum creatinine at regular intervals to ensure normal renal function. Avoiding or decreasing dose of nephrotoxins and contrast media can be done.
Primary Prevention
Primary Prevention
- Effective measures for the primary prevention of acute tubular necrosis include:
- Identifying individuals who are at risk for developing acute tubular necrosis. Promptly treating conditions that can lead to decreased renal perfusion and/or decreased oxygen to the kidneys can reduce the risk of acute tubular necrosis. These include:[1]
- Patients who are undergoing for major surgery such as cardiac or abdominal surgery
- Marked hypovolemia
- Severe hypotension
- Acute pancreatitis
- shock and sepsis
- Chronic renal disease
- Critically ill and hospitalized individuals
- Diabetes mellitus
- Monitor serum creatinine and urine output regularly in high-risk individuals.
- Avoiding or decreasing daily dose of nephrotoxins[2]
- Maintain volume status to ensure adequate renal blood flow by proper hydration or isotonic fluid administration.
- Contrast media-induced acute tubular necrosis may be prevented with administration of isotonic saline along with radiocontrast substance.[3]
- Identifying individuals who are at risk for developing acute tubular necrosis. Promptly treating conditions that can lead to decreased renal perfusion and/or decreased oxygen to the kidneys can reduce the risk of acute tubular necrosis. These include:[1]
References
References
- ↑ Norris MK (1989). “Acute tubular necrosis: preventing complications”. Dimens Crit Care Nurs. 8 (1): 16–26. PMID 2920655.
- ↑ Pazhayattil GS, Shirali AC (2014). “Drug-induced impairment of renal function”. Int J Nephrol Renovasc Dis. 7: 457–68. doi:10.2147/IJNRD.S39747. PMC 4270362. PMID 25540591.
- ↑ Mueller C, Buerkle G, Buettner HJ, Petersen J, Perruchoud AP, Eriksson U, Marsch S, Roskamm H (February 2002). “Prevention of contrast media-associated nephropathy: randomized comparison of 2 hydration regimens in 1620 patients undergoing coronary angioplasty”. Arch. Intern. Med. 162 (3): 329–36. PMID 11822926.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]